C4u

Cefpodoxime-Clavulanic acid is a combination of two drugs and is effective against multiple infection types. Clavulanic acid component protects degeneration of cefpodoxime in presence of beta-lactamase enzymes and increases the antibiotic spectrum.

Clavulanic acid in cefpodoxime-Clavulanic preparation prevents the resistance to Cefpodoxime that may increase with continuous usage of the drug. It has shown effectiveness against multiple Gram-positive and Gram-negative bacteria and is generally well tolerated.

ব্যবহার

URTIs

-Pharyngitis

-Tonsillitis

LRTIs

-Acute exacerbations of chronic bronchitis

-Acute community acquired pneumonia

SSTIs

UTIs

-Cystitis

-Uncomplicated urinary tract infections

Enteric fever

General gonorrhea and rectal gonococcal infections.

C4u এর দাম কত? C4u এর দাম

সুচিপত্র

• কাজ
• খাওয়ার নিয়ম
• পার্শ্বপ্রতিক্রিয়া
• সতর্কতা
• মিথস্ক্রিয়া
• গর্ভাবস্থাকালীন ব্যবহার
• তীব্র ওভারডোজ
• অন্যান্য ওষুধের সাথে প্রতিক্রিয়া
• বৈপরীত্য
• সংরক্ষণ

খাওয়ার নিয়ম / ব্যবহারের নিয়ম

C4u খাওয়ার নিয়ম / ব্যবহারের নিয়ম

Pharyngitis or tonsillitis:- (Duo-5 LS) 100 mg 12 hourly for 5 to 10 days

Uncomplicated urinary tract infections: (Duo-5 LS) 100 mg 12 hourly for 7 days

Complicated urinary tract infections: (Duo-5) 200 mg 12 hourly for7 days

Acute community acquired pneumonia: (Duo-5) 200 mg 12 hourly for 14 days

Acute bacterial exacerbations of chronic bronchitis: (Duo-5) 200 mg 12 hourly for 10 days

Uncomplicated gonorrhea and rectal gonococcal infections: (Duo-5) single dose

Skin and skin structure infections: (Duo-5) 200-400 mg 12 hourly for 7 to 14 days

Acute maxillary sinusitis: (Duo-5) 200 mg 12 hourly for 10 days

Enteric fever: (Duo-5) 200 mg 12 hourly for 7 to 14 days

Patients with renal dysfunction: For patients with severe renal impairment (< 30 ml/min creatinine clearance), the dosing intervals should be increased to 24 hourly. In patients maintained on hemodialysis, the dose frequency should be 3 times/week after hemodialysis.

Patients with cirrhosis: Cefpodoxime pharmacokinetics in cirrhotic patients (with or without ascites) is similar to those in healthy subjects. Dose adjustment is not necessary in this population.

পার্শ্বপ্রতিক্রিয়া

It has very few side effects. The side effects include diarrhoea, nausea, skin and vaginal fungal infection, vulvo-vaginal infections, abdominal pain and headache.

সতর্কতা

Cross hypersensitivity in penicillin sensitive patients, leading to serious acute hypersensitivity reactions may need treatment with epinephrine along with other emergency measures such as intravenous fluids, oxygen, airway management and intravenous antihistamine, as clinically indicated.

মিথস্ক্রিয়া

Probenecid: Renal excretion of Cefpodoxime proxetil was inhibited by Probenecid and resulted in an approximately 31% increase in AUC.

Nephrotoxic drugs: Close monitoring of renal function is advised when Cefpodoxime proxetil is administered concomitantly with compounds of known nephrotoxic potential.

গর্ভাবস্থাকালীন ব্যবহার

Pregnancy

Cefpodoxime is pregnancy category B. And Clavulanic acid is pregnancy category B.

বৈপরীত্য

It is contraindicated in patients with a known allergy to cefpodoxime and clavulanic acid or to the cephalosporin group of antibiotics.

অতিরিক্ত সতর্কতা

Patients with renal dysfunction: For patients with severe renal impairment (< 30 ml/min creatinine clearance), the dosing intervals should be increased to 24 hourly. In patients maintained on hemodialysis, the dose frequency should be 3 times/week after hemodialysis.

Patients with cirrhosis: Cefpodoxime pharmacokinetics in cirrhotic patients (with or without ascites) is similar to those in healthy subjects. Dose adjustment is not necessary in this population.

তীব্র ওভারডোজ

অন্যান্য ওষুধের সাথে প্রতিক্রিয়া

Probenecid: Renal excretion of Cefpodoxime proxetil was inhibited by Probenecid and resulted in an approximately 31% increase in AUC.

Nephrotoxic drugs: Close monitoring of renal function is advised when Cefpodoxime proxetil is administered concomitantly with compounds of known nephrotoxic potential.

সংরক্ষণ

Store in cool and dry place. Keep away from children.